The University of Texas at Dallas School of Behavioral and Brain Sciences

Theodore J. Price

Professor
Area Head, Cognition and Neuroscience
Program Head, Cognition and Neuroscience PhD
Eugene McDermott Professor

Research Interests

The molecular mechanisms that cause pain to become chronic; developing therapeutics to target these mechanisms

Curriculum Vitae

Biography

Dr. Theodore Price is one of the foremost researchers in understanding how neuronal plasticity alters the way the brain receives nociceptive information from the sensory system and how this relates to chronic pain in human patients. Dr. Price has discovered several novel targets that regulate the excitability of sensory neurons after injury and that mediate plasticity in the central nervous system that cause pain to become chronic. Dr. Price’s work has been published in numerous scientific journals and his research program has been supported by the National Institutes of Health and the Migraine Research Foundation. He serves as an editor for several leading industry journals and received the Patrick D. Wall Young Investigator Award from the International Association for the Study of Pain. Dr. Price also received the John C. Liebeskind Early Career Scholar Award from the American Pain Society, the Buhrmester Rising Star Award from UT Dallas, and has been named a permanent member of the NIH Somatosensory and Pain Study Section. Dr. Price earned his bachelor’s degree from UT Dallas and his doctoral degree in pharmacology from the University of Texas Health Science Center at San Antonio.

Recent and Selected Representative Publications

Articles in Peer-Refereed Journals

North RY, Li Y, Ray P, Rhines LD, Tatsui CE, Rao G, Johansson CA, Zhang H, Kim YH, Zhang B, Dussor G, Kim TH, Price TJ, Dougherty PM (2019) Electrophysiological and transcriptomic correlates of neuropathic pain in human dorsal root ganglion neurons. Brain. 142(5) 1215-1226.

Megat S, Ray PR, Tavares-Ferreira D, Moy JK, Sankaranarayanan I, Wangzhou A, Fang Lou T, Barragan-Iglesias P, Campbell ZT, Dussor G, Price TJ (2019) Differences between dorsal root and trigeminal ganglion nociceptors in mice revealed by translational profiling. Journal of Neuroscience, 39(35) 6829-6847.

Shiers S, Mwirigi J, Pradhan G, Kume M, Black B, Barragan-Iglesias P, Moy JK, Dussor G, Pancrazio JJ, Kroener S, Price TJ (2020) Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK. Neuropsychopharmacology, 45(3) 524-533.

Ruhl CR, Pasko BL, Khan HS, Kindt LM, Stamm CE, Franco LH, Hsia CC, Zhou M, Davis CR, Qin T, Gautron L, Burton MD, Naik DK, Dussor G, Price TJ, Shiloh MU (2020) Mycobacterium tuberculosis sulfolipid-1 activates nociceptive neurons and induced cough. Cell, 181(2) 293-305.

Barragan-Iglesias P, Franco-Enzastiga U, Jeevakumar V, Shiers S, Wangzhou A, Granados-Soto V, Campbell ZT, Dussor G, Price TJ (2020) Type I Interferons act directly on nociceptors to produce pain sensitization: implications for viral infection-induced pain. Journal of Neuroscience. 40(18) 3517-3532.