The University of Texas at Dallas School of Behavioral and Brain Sciences

Sven Kroener

Associate Professor

Research Interests

Physiology of the prefrontal cortex as it relates to schizophrenia and drug addiction

Curriculum Vitae

Contact

Email: [email protected]
Phone: 972-883-2039
Office: BSB_10.514
Campus Mail Code: BSB 14
Website: Cellular and Synaptic Physiology Lab and Center for Advanced Pain Studies

Biography

Dr. Sven Kroener is known for his research into animal models of schizophrenia and drug addiction. Recent projects look at vagus nerve stimulation (VNS) as a tool to increase extinction from drug seeking and to prevent relapse, and how alcohol addiction affects cognitive flexibility. All of these projects use a combination of behavioral, electrophysiological, and immunohistochemical techniques. Previous work in the lab also investigated changes in the prefrontal cortex that occur in a developmental model of schizophrenia which uses NMDA receptor antagonism to affect the function of GABAergic interneurons. Dr. Kroener has been continuously funded by extramural grants from NIH, as well as intramural grants from UTD. Dr. Kroener earned his master’s and doctoral degrees at the Ruhr-University in Bochum, Germany.

Recent and Selected Representative Publications

Recent Articles in Peer-Refereed Journals

Phensy A, Lindquist KL, Lindquist KA, Bairuty D, Gauba E, Guo L, Tian J, Du H, Kroener S (2020) Deletion of the mitochondrial matrix protein cyclophilin-D prevents parvalbumin interneuron dysfunction and cognitive deficits in a mouse model of NMDA hypofunction. J Neurosci 5;40(32):6121-6132. doi: 10.1523/JNEUROSCI.0880-20.2020.

Childs JE, Kim S, Driskill CM, Hsiu E, Kroener S (2019) Vagus nerve stimulation during extinction learning reduces conditioned place preference and context-induced reinstatement of cocaine-seeking. Brain Stimulation pii: S1935-861X(19)30283-9. doi: 10.1016/j.brs.2019.07.001.

Pradhan G, Melugin P, Wu F, Fang HM, Weber R, Kroener S (2018) Calcium chloride mimics the effects of acamprosate on cognitive deficits in chronic-alcohol exposed mice. Psychopharmacol. 235(7), 2027-2040. doi.org10.1007/s00213-018-4900-1.

Childs JE, DeLeon J§, Nickel E§, Kroener S (2016) Vagus nerve stimulation reduces cocaine-seeking and alters plasticity in the extinction network. Learning Mem. 24(1):35-42. doi: 10.1101/lm.043539.116.